2026 –  至今     教授， 南京大学 生物医学工程学院

2016 – 2025     教授， 南京大学 现代工程与应用科学学院

2011 – 2015     博士后，康奈尔医学院卫理公会医院

2005 – 2010      理学博士，中国科学院长春应用化学研究所    

2001 – 2005      理学学士，武汉大学

成果：

国家海外高层次引进人才（2015年），江苏省双创人才（2018年），江苏省双创团队（2020年）。先后承担国家自然科学基金面上项目、青年项目，国家重点研发计划，江苏省重点研发计划等重要研究任务，以通讯作者/第一作者发表SCI论文100余篇，共计被他人引用8000余次，单篇最高他引2000余次。

发表：

1.   Luo W, Gao Y,, Feng S, He B, Li J, Yang J, Xue B, Cao Y, Hu T,* Song Y. * A Mechanophenotyping Chip for High-Throughput Detection of Metastatic Bacteria-Infected Circulating Tumor Cells. Nat. Commun. 2026，10.1038/s41467-025-68152-y.

2.     Qin S, Wang Q, Zhang Z, Gu J, He G, Zeng F, Chen R, He B, Wang Y, Wang M, Song Y.*Metabolic Hijacking by Engineered Probiotics Reprograms Tumor Metabolism and Immune Microenvironment. J. Am. Chem. Soc. 2025 ，147, 38180.

3.     Liu Z, Luan X, Lu Q, Qin S, Zeng F, Li Z, He B, Song Y.* Reactive oxygen species responsive nanomotors for gene edited metabolic disruption，Nat. Commun.2025，16，4708

4.     Pan Y, Zeng F, Luan X, He G, Qin S, Lu Q, He B, Han X, Song Y.*Polyamine-Depleting Hydrogen-Bond Organic Frameworks Unleash Dendritic Cell and T Cell Vigor for Targeted CRISPR/Cas-Assisted Cancer. Adv. Mater. 2025，e2411886

5.     Zhou D, Zhang Z, Pan L, Wang Y, Yang J, Gao Y, Song Y. * Sucrose-Powered Liposome Nanosensors for Urinary Glucometer-Based Monitoring of Cancer. Angew. Chem. Int. Ed.2024，202404493.

6.     Feng S, Zhang Y, Hou C, Liu Y, Gao Y, * Song Y.*, Luo J. * A temperature-responsive dual-hormone foam nanoengine improves rectal absorptivity of insulin-pramlintide for diabetes treatment. Sci. Adv. 2024, 10, eadn8695.

7.     Zhang Z, Zhou D, Li Z, Luan X, Yang J, * Tang S, * Song Y. * A Nanoinhibitor Targeting cGAS-STING Pathway to Reverse the Homeostatic Imbalance of Inflammation in Psoriasis. Angew. Chem. Int. Ed. 2023，e202316007.

8.     Feng S, Zhang Y, Gao Y, Liu Y, Wang Y, Han X, Zhang T, Song Y. * A Gene-Editable Palladium-Based Bioorthogonal Nanoplatform Facilitates Macrophage Phagocytosis. Angew. Chem. Int. Ed. 2023，e202313968.

9.     Yang J, Yang K, Du S, Luo W，Wang C, Liu H, Liu K, Zhang Z, Gao Y, Han X*,  Song, Y.* Bioorthogonal Reaction‐Mediated Tumor‐Selective Delivery of CRISPR/Cas9 System for Dual‐Targeted Cancer Immunotherapy. Angew. Chem. Int. Edit.  2023, e 202306863.

10.   Gao, Y.; Wang, Y.; He, B.; Pan, Y.; Zhou, D.; Xiong, M.; Song, Y.* An Enzyme-Loaded Metal-Organic Framework-Assisted Microfluidic Platform Enables Single-Cell Metabolite Analysis. Angew. Chem. Int. Ed.  2023, e202302000.

11.   Xu Q, Pan Y, Liu X, Gao Y, Luan X, Zeng F, Zhou D, Long W, Wang Y, Song Y. *Hypoxia-Responsive Platinum Supernanoparticles for Urinary Microfluidic Monitoring of Tumors. Angew. Chem. Int. Ed. 2022, 61(14): e202114239.

12.   Li X, Pan Y, Chen C, Gao Y, Liu X, Yang K, Luan X, Zhou D, Zeng F, Han X, * Song Y.* Hypoxia‐Responsive Gene Editing to Reduce Tumor Thermal Tolerance for Mild‐Photothermal Therapy. Angew. Chem. Int. Ed. 2021, 60，21200-21204.

13.   Pan Y, Yang J, Luan X, Liu X, Li X, Yang J, Huang T, Sun L, Wang Y, * Lin Y, * Song Y.* Near-infrared upconversion–activated CRISPR-Cas9 system: A remote-controlled gene editing platform. Sci. Adv. 2019, 5, eaav7199.

14.  Lu Q, Ye C, Mao W, Zeng F, Liu Z, Chen R, Cheng X, Gao Y, Wang M, Liu M, *  Tang S, *  Song Y*. Targeting Senescent Alveolar Type 2 Cells with a Gene-Editable FePt Dual-Atom Catalyst for Mitigating Idiopathic Pulmonary Fibrosis. ACS Nano. 2025. 19，23162-23176.

15.  Qin S, Liu Y, He G, Yang J, Zeng F, Lu Q, Wang M*, He B*, Song Y*. Spatiotemporal Delivery of Dual Nanobodies by Engineered Probiotics to Reverse Tumor Immunosuppression via Targeting Tumor-Derived Exosomes. ACS Nano. 2024, 18, 26858-26871

16.  He G, Pan Y, Zeng F, Qin S, Luan X, Lu Q, Xie C, Hu P, Gao Y, Yang J, He B, Song Y. * Microfluidic Synthesis of CuH Nanoparticles for Antitumor Therapy through Hydrogen-Enhanced Apoptosis and Cuproptosis. ACS Nano. 2024,18, 9031-9042.

17.  Zeng F, Pan Y, Wu M, Lu Q, Qin S, Gao Y, Luan X, Chen R, He G, Wang Y,* He B, * Chen Z, * Song Y. * Self-Metallized Whole Cell Vaccines Prepared by Microfluidics for Bioorthogonally Catalyzed Antitumor Immunotherapy. ACS Nano. 2024,18, 7923-7936. 

18.  Zhang, Z.; Zhou, D.; Luan, X.; Wang, X.; Zhu, Z.; Luo, W.; Yang, J. *; Tang, S. *; Song, Y.* Biodegradable Hollow Nanoscavengers Restore Liver Functions to Reverse Insulin Resistance in Type 2 Diabetes. ACS Nano 2023, 17, 9313-9325.

19.   Pan, Y.; Luan, X.; Gao, Y.; Zeng, F.; Wang, X.; Zhou, D.; Li, W.; Wang, Y. *; He, B. *; Song, Y.* In-Tumor Biosynthetic Construction of Upconversion Nanomachines for Precise Near-Infrared Phototherapy. ACS Nano 2023, 17, 4515-4525.

20.   Zhou, D.; Yin, Y.; Zhu, Z.; Gao, Y.; Yang, J.; Pan, Y.; Song, Y.* Orally Administered Platinum Nanomarkers for Urinary Monitoring of Inflammatory Bowel Disease. ACS Nano 2022, 16, 18503-18514.