2020年博士毕业于中国科学院国家纳米科学中心，此后分别在新加坡国立大学生物医学工程系和哈佛大学医学院开展博士后研究。入选2024年度国家（海外）优秀青年人才基金项目。担任Advanced Therapeutics杂志客座编辑及The Innovation, Life Medicine等多个杂志的青年编委，担任Nature Communications, ACS Nano等杂志的独立审稿人。

课题组研究方向涵盖药物递送、纳米医学、免疫治疗、生物材料、生物医药和技术等多个交叉领域，针对临床疾病特点和现有治疗手段所存在的挑战，综合运用生物医学工程、药学、高分子材料、物理化学以及人工智能等手段，提出实用性解决策略和方案

作为通讯/第一作者在Nature Biomedical Engineering, Advanced Materials, ACS Nano, Advanced Therapeutics等期刊发表多篇研究论文。主要成果被Nature Materials, Advanced Science, 中国科学报，中国科学院等期刊和机构专文评述和报道，授权多项国际PCT专利和国家专利/标准。荣获首届智能生物制造与前沿国际论坛暨创新创业大赛优秀青年科学家奖。

发表文章：

1. Li X.†, Gong N.†,*, Tian F., Zhang S, Zhang Y., Wang Y., Qing G., Wang Y., Li F., Xu Y., Zhang L., Wang J., Ni Q., Gan  Y., Gu C., Jiang H., Huang X., Shi X., Zhang T., Wu Y.* & Liang X. -J.* Suppression of Cytokine Release Syndrome During CAR-T Cell Therapy via a Subcutaneously Injected Interleukin-6-Adsorbing Hydrogel. Nature Biomedical Engineering, 2023, 7, 1129-1141. (link )

2. Li X.†, Xu X.†, Wang K.†, Chen Y., Zhang Y., Si Q., Pan Z., Jia F., Cui X., Wang X., Deng X., Zhao Y., Shu D., Jiang Q.*, Ding B.*, Wu Y.* & Liu R.* Fluorescence-Amplified Origami Microneedle Device for Quantitatively Monitoring Blood. Advanced Materials, 2023, 2208820. Frontispiece. (link )

3. Li X.†, Bottini M.†, Zhang L., Zhang S., Chen J., Liu L, Rosato N, Ma X, Shi X, Wu Y.*, Guo W.* & Liang X.-J.* Core-Satellite Nanomedicines for in vivo Real-Time Monitoring of Enzyme-Activatable Drug Release by Fluorescence and Photoacoustic Dual-Modal Imaging. ACS Nano, 2019, 13, 176-186. (link )

4. Li X.†, Pan Z.†, Xiang C., Yuan Y., Chen J., Qing G., Ma J., Liang X.-J.*, Wu Y.* & Guo W.* Structure Transformable Nanoparticles for Photoacoustic Imaging-Guided Photothermal Ablation of Tumors via Enzyme-Induced Multistage Delivery. Chemical Engineering Journal, 2021, 421, 127747.(link )

5. Li X.†, Wang X.†, Zhao C., Shao L., Lu J., Tong Y., Chen L., Cui X., Sun H., Li M.*, Deng X.* & Wu Y.* From One to All: Self-Assembled Theranostic Nanomedicines for Tumor Targeting Imaging and Programmed Photoactive Therapy. Journal of Nanobiotechnology, 2019, 17, 23. (link )

6. Li X.†, Shou Y.†, Tay A.* Hydrogels for Engineering Immune System. Advanced NanoBiomed Research, 2021, 2000073. (link )

7. Huang X.†, Li X.†, Tay A.* Advances in Techniques to Characterize Cell-Nanomaterial Interaction (CNI). Nano Today, 2024, 55, 102149. (link )

8. Li C.†, Li X.†, Li S., Weng Y., Wang K., Zhang T., Chen S, Lu X., Jiang Y., Xu J.* & Liang X.-J.* Development and Validation of a Method for Determination of Encapsulation Efficiency of CPT-11/DSPE-mPEG2000 Nanoparticles. Medicinal Chemistry, 2016, 6, 345-348. (link )

9. Zhu M., Tay A.*, Li X.* Immune-Engineering in the AI Era: from Fundamental Research to Clinical Translation. Advanced Therapeutics, 2025, 08, e00087 (link ) 

10. Xu C.†, Gao Y., Zhang X., Jia F.*, Pan Z., Li M., Wang W., Li X.*, Wu Y.*Polydopamine-Integrated Nanomedicine through Dual Metabolic Intervention with Enhanced Photothermal Therapy against Triple-Negative Breast Cancer. Advanced Therapeutics, 2025, 08, e00570 (link )